NU FS356 Lecture Notes - Lecture 2: Diabetes Mellitus Type 2, Sickle-Cell Disease, Apolipoprotein E
11 Feb 2019
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Document Summary
Nutrigenet certain genes are susceptible to a certain nutrient or environment. Genetic makeup can aid in this personalized diet . Na is to rna which is translated to a protein. Genot#e+phen0t4pe depending on the translation even after being turned into a protein. Pe is dependent on the dominant or recessiveness of the gene remember. , genotype aabb differences of genetic phenotype , green + wrinkled arising from polymorphism and now they modify dietary effects . Change in the gene that results in a certain effect. Ost commonly ( at least in this context. " a low or nonfunctioning protein have other variations. Exam in sickle cell disease , glutamic acid is substituted with valine. At heterozygous for the hb i has alleles some disc shaped and some with potential to sickle ( no clinical symptoms ) Rbcs that can sickle ( sickle cell disease ) Overexpression associated with dyslipidlmia , impaired glucose metabolism , type 2 diabetes.
