NU FS356 Lecture Notes - Lecture 17: Chromosome, Oxidative Phosphorylation, Catalase
Document Summary
O2- or h2o2 that are generated by the mitochondria during respiration and oxidative phosphorylation damage the proteins, lipids and dna. Antioxidants are important to hunt down and satisfy the missing electron of the radicals to help longevity. The programmed cell death aka gene directed suicide in response to internal or external stimuli: neuroendocrine theory of aging, this relates to the decreased functioning neurons and the associated hormones as a central part of aging. Stressor is sensed by hypothalamus which then releases hormones the act on different tissues to insure we react appropriately to given stimuli. It is suspected that we either are desensitized to these hormones or we release less. Also, responsible for changes in hunger and thirst. The components of this theory include: hypothalamic-pituitary-adrenal axis (hpa axis): the master regulator of development and growth, puberty, control of the reproductive system, metabolism and maintenance of homeostasis. 2: the reduced resistance to infectious diseases cause chronic and deathly conditions.