BIOL 315 Lecture Notes - Lecture 17: Coeliac Disease, Gluten, Sorption

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pucegerbil279

21 Mar 2020

School

University of Alberta

Department

Biology (Biological Sciences)

Course

BIOL 315

Professor

William Allison

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Document Summary

Ghrelin : secreted by the cells in the lining of the stomach the appear. Pyy 1 peptide tyrosine tyrosine ) : released by the cells of the ileum and colon. Glutenin . avwmposite storage protein found in the endosperm w| starch in cereal grains such as wheat. Pwiamine are high in the amino acid pwline. Gluten has visw elastic properties making dough elastic and produces a chewy texture . Coeliac disease is caused by a gene mutation in two chromosomes. Human leucocytes antigen is a protein responsible for initiation the immune of response ; mutation in these result in an autoimmune response. To gluten . where the body "s defense system attaches. The cells in the villi leak ( primarily ) causing gastrointestinal problems , the rather cells into. Malak sorption , diarrhea leaky got syndrome( contents cells ) )

Related Questions

Some of the excess calories we consume are stored as fat glycogen. Excess storage can lead to obesity, which is one of the worldwide health issues in humans. Body weight is regulated by complex brain circuitry involving peripheral factors that primarily work in the brain. Please answer the following questions:

a) John is 30 years old. His height is 170cm and body weight is 88kg. Based on his BMI, is John is obese or not? (1.5 marks)

b) The ob/ob mutant mouse become obese due to mutation in the gene responsible for the production of a polypeptide hormone that affects the adipose tissue mass. What is the name of the hormone and where is produced in the body? (1.5 marks)

c) Pleases explain how the hormone regulates body weight, including the major brain site of its action (1 mark), its effect on appetite (2 marks) and the contribution of brown adipose tissue to the weight regulation. (2 marks)

d) In addition to this hormone, a peptide hormone produced by the gastrointestinal tract also contributes to regulating appetite and energy expenditure. The hormone was discovered by a Japanese group in 1990s. What is the name of the hormone? (0.5 mark) What is the main effect of this gut hormone on food intake, body weight and hunger signals? (1.5 marks)

Which of the following is a feature of fat metabolism?

Select one:

A. Triglycerides in the blood must first be broken down to monoglycerides, fatty acids, and glycerol prior to uptake by the adipose cells

B. Cholesterol is stored primarily on the surface of veins

C. High-density lipoproteins represent the major transport vehicle for delivering fat to the adipose cells

D. Fat storage is highly efficient due to the rapid uptake of the intact triglyceride molecule by adipose cells

1. Leptin "resistance" would result in ____________________.

a. decreased satiety

b. decreased appetite

c. lower circulating leptin

d. higher concentrations of ghrelin

2. A drawback of using BMI measurements is that

a. BMI does not account for body frame size

b. BMI has not been formally adopted by clinicians or policy makers

c. BMI does not account for differences in body composition

d. BMI overcompensates for racial differences in fat content

3. Metabolic conditions, such as __________________, may be a common link between hypertension, obesity, diabetes, and CHD.

a. hypothyroidism

b. hyperthyroidism

c. insulin resistance

d. Cushing's syndrome

4. High blood pressure

a. is normal and doesn't tax the heart

b. can lead to other cardiovascular diseases

c. leads to a smaller, atrophied heart

d. is more common in white Americans

5. Heart attacks

a. almost always result in instant death

b. can be mild, moderate, or severe

c. do not result in necrosis of heart tissue

d. can only be detected using an arteriogram

6. An ECG can help diagnose

a. low hemoglobin

b. high blood pressure

c. arrhythmias

d. high afterload on the heart

7. A graded exercise test should include

a. a test

b. a lactate threshold blood test

c. a calculation of aerobic power

d. an exercising ECG for those at high risk

BIOL 315 Lecture Notes - Lecture 17: Coeliac Disease, Gluten, Sorption

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