BIOCH200 Lecture 2: Oxidative phosphorylation: The action of ATP synthase
9 Dec 2017
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Document Summary
The diagram shows the structure of atp synthase: There are two parts of an atp synthase: fo : it is the transmembrane portion through which protons pass. It is inhibited by a compound called oligomycin: f1: it s=is the catalytic portion that catalyses the production of atp from adp and pi. The free energy change from the redox reactions that fuel atp synthase work by rotating the shaft at f1. Each complete rotation form 3 molecules of atp. The ultimate electron acceptor of the electron transport chain is oxygen. The newly synthesised atp is transported out of the mitochondrial matrix. Adp and pi produced in cells is again transported to the matrix. It is all done by the adenine nucleotide translocase and the pi-h+ symport. In the adenine nucleotide translocase, one atp is pumped for every adp pumped in. In the pi-h+ symport, pi is transported in for atp formation along with a proton.
