BIOCH200 Lecture Notes - Lecture 25: Flavin Mononucleotide, Oxidative Phosphorylation, Electron Transport Chain

• School: University of Alberta
• Department: Biochemistry
• Course: BIOCH200
• Professor: Jonathan Parrish

Document Summary

Biochem 200 - lecture #25 - oxidative phosphorylation. Introduction: generates lots of reduced cofactors through oxidation, oxidative phosphorylation requires something to be reduced (example, oxygen to water, the citric acid cycle contains many catabolic processes. Breaks down larger molecules into smaller building units. Releases and stores temporarily high energy molecules [ie. phosphoanhydride bonds] Re-oxidation of the cofactors used to generate atp. Oxidative phosphorylation: contains 2 separate but connected processes. The processes are linked through a proton gradient across the mitochondrial membrane: these 2 processes are 2 different primary transport systems. Nadh (cid:1372) nad+ + h+ + 2e- 4h+ + 4e- + o2 (cid:1372) 2h2o (or can also halve the equation) Adp + pi + h+ (cid:1372) atp + h2o. Uses the protons to drive the synthesis of atp. Overview: atp synthesis: converting potential energy to chemical reactions. This is because the complexes aren"t very good with proteins.