NURS 3550H Lecture Notes - Lecture 12: Mydriasis, Adrenergic, Hemostasis
31 Oct 2018
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Receptors: adrenergic, alpha (bind well with ne, beta (bind well with epi, alpha1, alpha2, beta1, beta2. Adrenergic agonists: mimic effects of sns stimulate r effects depend on which r stimulated. Clinical impact of adrenergic receptor stimulation: alpha-1, vasoconstriction. Decongestion, hemostasis, bp: mydriasis, alpha-2, beta-1, beta-2, bp, pain, constrict prostatic capsule, hr, contractility, conductivity, renin release, bronchodilation, hyperglycemia, uterine relaxation, skeletal muscle stimulation, direct-acting agonist, d binds to r and has effect. Indirect-acting agonist: d inhibits synthetic enzyme, increases ne levels, mixed-acting agonist, d does both. Effects: alpha-r effects ( 1, beta-r effects, all systems affected, fight/flight, cvs, heart, 1 inc hr inc contractility, auto conductance, blood vessels, 1, 2, kidney, 1, lungs, 2, uterus, 2, gi tract, relax, bladder, relax, blood glucose. Therapeutic indications: status asthmaticus, anaphylaxis, cardiac arrest. Adverse effects: cns, cvs, lungs, dysrhythmias due to b1 stimulation, ht crisis, cerebral hemorrhage, b2 relax bronchioles, dyspnea, liver / blood glucose, hyperglycemia.
