BISC 313 Lecture Notes - Lecture 4: Queen'S Privy Council For Canada, Histopathology, Regression Analysis

• School: Simon Fraser University
• Department: Department of Humanities Biological Sciences
• Course: BISC 313
• Professor: Vicki Marlatt

Document Summary

Acute and chronic single species toxicity assays. Non-threshold toxicant: adverse effect increases with dose. Essential nutrient: no adverse effect in a specific range. Threshold toxicant: adverse effect upon reaching a specific amount. Hormesis: a biphasic dose response with a low dose of a toxicant causing stimulation or beneficial effect and a high dose inhibitory or toxic effect: only living material can measure toxicity. In vitro and in silico methods not sufficient alone to estimate toxicity of chemicals: many advancements. In vivo is the best: canadian council on animal care, highest standards of animal ethics and care are valued and assured in all animal-based science conducted throughout canada. 3 main categories used by agencies in evaluation & regulation of toxic chemicals: human epidemiology, human controlled clinical exposure, plant & non-human animal toxicity tests*** what this course focuses on. Often combined with above to provide supportive info: