BIOL354 Lecture Notes - Lecture 2: Rotary Evaporator, Nonpoint Source Pollution, Urban Runoff

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Lecture 2: contaminants from source to receptor to impact. Contaminant fate studies: investigates the origins, concentrations, partitioning & persistence: e. g. Total [ssri] with increasing distances (highest @ point of release, dilutes as it travels, & accumulates meters downstream) (searching for [] that induce side effects) Contaminant effect studies: evaluates biotic & abiotic consequences of contaminant exposures: e. g. Mating behavior & egg production of japanese medaka (already @ the [] for negative effects to occur, monitors different effects compare to a normal control group). Contaminant movement: environment: abiotic simple diffusion, organisms: biotic bio-concentrated (water uptake) or bio-accumulated (water & food uptake). (higher [] in the organism relative to the environment) Food chain: bio-magnification in higher organisms (especially pcbs & dioxins). Accumulates more in adipose tissues than muscle tissues. Lipophilic drugs do not accumulate (except for synthetic estrogen, which can bind to a variety of receptors)

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