Practical Nursing PNP301 Lecture Notes - Lecture 9: Microcirculation, Magnetic Resonance Imaging, Dyslipidemia

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Target receptors: hormones as chemical messengers, negative feedback systems. They are lipids and enter the cell nucleus to initiate transcription directly. Nonsteroid: needs a secondary messenger system to activate transcription in the nucleus. The endocrine and nervous systems regulate metabolic activities: negative feedback system. Hormone release: most often controlled by negative feedback mechanisms, endocrine and nervous systems work together to regulate metabolic activities, complex system for some hormones. Secretion may be controlled by more than one mechanism: rate and timing of secretion may vary. Cyclic patterns: all disorders reflect impaired control or feedback. Excess hormone levels: tumor produces high levels, excretion by liver or kidney is impaired, congenital condition produces excess hormone. Deficit of hormone or reduced effects: tumor produces too little hormone. Inadequate tissue receptors present: antagonistic hormone production is increased, malnutrition, atrophy, surgical removal of gland, congenital deficit. Diagnostic tests: blood tests, check serum hormone levels, radioimmunoassay. Scanning, ultrasound, magnetic resonance imaging (mri: biopsy.

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