PAT 20A/B Lecture Notes - Lecture 8: Anterior Interventricular Branch Of Left Coronary Artery, Hyperlipidemia, Low-Density Lipoprotein

• School: Ryerson University
• Department: Pathotherapeutics
• Course: PAT 20A/B
• Professor: shirley

Document Summary

Particularly potent on large & small coronary arteries, causing redistribution of blood and o2 to previously ischemic myocardial tissue, reducing angina. Inhibits sodium potassium atpase, which makes more calcium available for contractile proteins = increased cardiac output, increased force of contraction, decreased hr, decreased av conduction speed. High doses can lead to plaque regression. constipation, diarrhea, flatus, heartburn, liver dysfunction, rhabdomyolysis. Seizures, bradycardia, shock, cardiac arrest, tachycardia, thrombocytopenia, respiratory distress, respiratory arrest, apnea. Assess muscle pain, tenderness, cpk (creatine phosphokinase) baseline (cid:224) if markedly increased may have to discontinue. Murmurs: sounds produced by turbulent blood flow through heart or walls of large arteries, normally result of cardiac abnormality, but can occur with normal cardiac structures, graded on 6 point scale of loudness and recorded as roman numeral ratio, time, location, pitch, position, characteristic and any other abnormal findings should be documented if one is heard.