PSYC 370 Lecture Notes - Lecture 11: Amyloid, Neurofibrillary Tangle, Diabetes Mellitus Type 2

• School: Queen's University
• Department: Psychology
• Course: PSYC 370
• Professor: Janet L Menard

Document Summary

Obesity large risk factor linked to type 2 diabetes where insulin receptors in the body are no longer sensitive to insulin. Some believe alzheimer"s may be type 3 diabetes where diet is related. Stage 1: long-term memory and cognitive function is still in-tact it is difficult for a doctor to tell whether this is alzheimer"s or clinical depression in the elderly. Stage 2: earliest long-term memories are the last one to disappear! Visuospatial impairments: example: older person with dementia cannot find their way home! Language impairments: trouble forming words, sentences, trouble understanding. Stage 3: impairments are so severe, may be completely confined to bed, lose control of bowel and bladders! In a normal brain, the gyri are nice and pulp, sulci are narrow. There is reduced cortical activity in an ad brain. Before, we couldn"t tell if ad until post-mortem analysis of the brain! B- amyloid plaques: build up in the extracellular space!