NURS 2003 Lecture Notes - Lecture 11: Renal Function, Venous Stasis, Pulmonary Valve

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Thrombus formation (clot) in deep veins usually lower extremity. Hypercoagulable states- pregnancy, inherited disorders, hormone replacement therapies. May embolize or lead to venous ulceration. Anticoagulation with heparin, low molecular weight heparin and warfarin. A bolus of material circulating in the bloodstream. Fat- common cause is break in long bone. Preload- pressure of the volume of blood in the ventricle on the ventricle walls just before ventricular contraction, at end of diastole. Afterload- resistance against which the ventricle has to push the blood. Co= hr (beats/ min) x stroke volume (l/beat) So bp= hr x sv/ foc x pvr (consider volume and force together) Hypertension- blood pressure should be lowered to less than 140/90 mmhg in most individuals. For those individuals with diabetes or chronic kidney disease, to less than 130/80 mhg. Anp increase the glomerular filtration rate (gfr) thus getting rid of excess volume. Anp also inhibits raa pathway to decrease volume and pvr.

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