PSYCH 1XX3 Lecture Notes - Lecture 8: Orexigenic, Saccharin, Leptin
22 Mar 2017
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Document Summary
The primary reason for hunger is low blood glucose levels. The brain cannot use fat energy stores for fuel, so regulating blood glucose is a top priority. Glucose is stored in the body as glycogen, which can be released in between meals. Some glycogen is stored in the muscles, but most of it is stored in the liver where it can be readily converted back into glucose. >this process is largely regulated by the pancreatic hormone insulin. Neuropeptide y stimulates high levels of activity in the hypothalamus, and this is associated with increased appetite and food seeking behaviours. Npy affects feeding behaviour similarly in sh, reptiles, birds, and other non-human mammals. Npy neurons can speci cally affect reward driven feeding for high calorie foods (ex sucrose) Npy action promotes unconditional and conditional behaviour (intake of saccharine is also increased, although it has no calories) The small intestine produces cholecystokinin, a hormone responsible for feelings of satiety.
