HTHSCI 2H03 Lecture 1: Module 1 - Core Concepts in Pharmacology
18 Sep 2018
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An equation describing how the ph of a solution affects the concentration of ionized and non-ionized acids in that solution. Pharmaceutical drugs are very weak acids or bases (in comparison to hcl and naoh) Acid: a compound that dissociates to produce a hydrogen cation (proton) *ah - an acid in its non-ionized or non-polar form. *a- - denotes an acid in its ionized or polar form. *basic drugs accept hydrogen cations (protons) in water. *b denotes a base in its non-ionized or non-polar form. *bh denotes a base in its ionized or polar form. An equation describing how the ph of a solution affects the concentration of ionized and. Used to illustrate where in the body an acidic drug will be absorbed after taking it orally. Only drugs in their non-ionized or neutral form can pass through plasma membranes and become absorbed. Plasma membranes are made up of a lipid-rich bilayer that is relatively non-polar.
