HTHSCI 1H06 Lecture Notes - Lecture 6: Cardiac Muscle, Heart, Perspiration
29 Mar 2018
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Document Summary
In shock, changes in any of these variables can result in a decrease supply of oxygen to the tissues. Increased basal metabolic rate (bmr) causes our body tissues to consume more oxygen: bmr is the rate in which oxygen is consumed by our cell and it largely regulated by thyroid hormone. Individuals that suffer from hyperthyroidism will have an increased tissue demand for oxygen and bmr will be elevated. By increasing body temperature, it causes our immune cells to become more metabolically active; working faster and more efficiently to clear an infection. Increased workload on the heart (sns, increase preload and afterload, physical activity, stress, etc. ) The cycle of shock: tissue hypoxia leads to a switch to anaerobic respiration, metabolic acidosis occurs when the heart need oxygen, fall in ph is detrimental to cardiac contractility, resulting in cardiac depression and reduction in cardiac output.
