HTHSCI 1H06 Lecture Notes - Lecture 6: Stroke Volume, Body Fluid, Extracellular Fluid
27 Mar 2018
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Describe the causes and classification of shock. Discuss the homeostatic mechanisms employed in response to shock. Discuss examples of shock in each class using a case-study approach. Shock occurs when the cardiovascular system fails to adequately perfuse cells, tissues, and organs, resulting in a widespread impairment of cellular metabolism and tissue function. Shock is not always associated with a decrease in bp, however as a general rule, to perfuse tissues with blood you need to generate a bp to keep blood moving around the cardiovascular system. Bp, is a function of cardiac output is systemic vascular resistance. As blood vessels constrict to increase systemic vascular resistance, blood flow through the vessels and to the tissues they serve will diminish: systemic vascular resistance. Function of blood viscosity, blood vessel length and blood vessel radius. Because systemic vascular resistance is related to radius4, it is the radius of the blood vessel that contributes the most to systemic vascular resistance.
