BIOLOGY 2B03 Lecture Notes - Lecture 8: Beta Oxidation, Leucine, Dominance (Genetics)
9 Apr 2018
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Document Summary
Inside the peroxisomes are dense regions that contain protein aggregates composed of almost exclusively of catalase. In animal cells it is responsible for cholesterol synthesis, the oxidation of toxins in the liver and in plants it is required for the conversion of fatty acids into carbs (as a catalyst) A major function of the peroxisome is the breakdown of long chain fatty acids into medium chain fatty acids (which are then sent to the mitochondria for further processing) through beta-oxidation. Hydrogen peroxide is a byproduct of the oxidation of fatty acids in the peroxisome, and its toxic to the cell. The catalase enzyme converts hydrogen peroxide into oxygen and water. By using a catalase antibody in combination with a fluorescent, we can identify peroxisomes and learn they moving around, change shape and undergo fission and fusion. Peroxisomal proteins are synthesized in the cytosol and transported to the peroxisome. Pmp70) are targeted to precursor membranes first to create a peroxisomal ghost.
