BIOLOGY 1A03 Lecture Notes - Lecture 3: Aminoacyl Trna Synthetase, Aminoacyl-Trna, Elongation Factor
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BIOLOGY 1A03 Full Course Notes
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Initiation factors: mrna, elongation factors, release factors, aminoacyl trna synthesis, ribosome (rrna and ribosomal proteins) trna trna. Transport amino acids to a growing polypeptide in the ribosome. Made up of a single rna strand ranging between 70-90 nucleotides. There is a large degree of complementarity (describes a relationship between 2 structures each following the lock- and-key principle. Results in many stretches of hydrogen bonding between complementary nucleotides. Allows formation of 4 double helical segments and 3 loops seen in trna. Whole trna molecules can also fold roughly into an l shaped structure. Anticodon region is a specific nucleotide triplet that forms complementary base pairs with a specific mrna codon that codes for a specific amino acid. Anticodons written in 3"-5" direction and align properly with mrna codons in the 5"-3" direction. At the 3" end, there is a protruding amino acid attachment site made up of a single stranded cca nucleotide sequence.