PHGY 209 Lecture Notes - Lecture 4: Extracellular Fluid, Fluid Compartments, Homeostasis

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The viability of cells depends on the relative constancy of the "internal environment" ("milieu. Movement of water and molecules distributed around different compartments of the body via cell membrane. Special mechanisms exist to transport other molecules that may not move well through the cell membrane. Phospholipid bilayer the: cystic fibrosis channels are put the into membrane to study the movement of ions through this channel, otherwise, you could have a bilayer with no movement through it. Cholesterol: ~40% of the non protein part of cell membrane, amphipathic (charged at different ends, but overall neutral) Inserted in phospholipid layer (in the tail region) provides stability, strength and rigidity the impermeability of: contributes membrane to, adds firmness, but enhances flexibility; prevents tails of the phospholipids from crystallizing. Make up most of cell membrane and are the functional units of the cell membrane. Integral: closely associated with phospholipids, mostly cross the membrane (trans membrane) larger than 10nm.

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