PHGY 209 Lecture Notes - Lecture 12: Deoxyribonucleotide, Transferase, Immunoglobulin M
14 Oct 2017
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The complement cascade (classic: constant regions of 2 antibody molecules in the antigen-antibody complex bind. Complement plays a role here e. g. enhances phagocytosis (c3 and c5 products) Sees antigen and fold itself around it. Antibody molecule selects the antigen to which it will bind. Bacteria block cell receptor cell dies. Cell sees little bacteria makes more antibodies. Makes so much that some comes off and circulates in blood. Assumed all antibody molecules were genetically programmed before birth. * mature b cell returns to the bone marrow from the regional lymph node (stimulated) where it will proliferate and become a plasma cell, loses its surface immunoglobulin and secretes antibodies. Initiation of the antibody production by the humoral immune response, the dendritic cell has now produced a peptide that shows on the surface of its mhc class ii molecule. The next molecule is the th2 cell (helper cell 2) combines at two points (t-cell receptor with.
