BIOL 202 Lecture Notes - Lecture 1: Polycystic Kidney Disease, Factor Viii, Artificial Insemination
Document Summary
Lectures 1 & 2 (chapters 1*, 2, 3) Overview of genetics past and present. Mendel"s law of independent assortment (2nd law) Each cell contains chromos and chromos contain genes. Genetics can be thought of as a system of biological information transfer. Information has to replicate and be passed on from cell to cell during growth from parent to progeny: the information system is not entirely error-proof leading to the generation of diversity. Information translated into a blueprint for development (rna = blueprint proteins: rna gives us the phenotype. In the nucleus: dna undergoes transcription to form the primary rna transcript undergoes rna processing to produce mature rna (splicing of introns which are sequences of non-coding rna) gets transported out to the cytoplasm. In the cytoplasm: ribosomes attach to the mrna translation into proteins. Hemophilia a = missing factor viii in the clotting cascade. Hemophilia b = missing factor ix in the clotting cascade.