BIOL 115 Lecture Notes - Lecture 22: Spatial Memory, Doxycycline, Fear Conditioning

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28 Nov 2017
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In order to use spatial memory, an individual has to use global cues. In order to dete(cid:396)(cid:373)i(cid:374)e (cid:449)hethe(cid:396), sa(cid:455), a s(cid:395)ui(cid:396)(cid:396)el"s hippo(cid:272)a(cid:373)pus is (cid:374)e(cid:272)essa(cid:396)(cid:455) fo(cid:396) it to fi(cid:374)d his hidde(cid:374) (cid:374)uts, you would have to remove it and see if the squirrel can still find his nuts. If you just look at whether the hippocampus is active when the squirrel is looking for his nuts, this would tell you whether or not the hippocampus is involved but nothing about whether it is necessary. Because scientists have the best genetic control over mice. To get a mouse to remember something, you need to condition them. You start with a neutral stimulus, like a bell. You can do conditioning by pairing all kinds of stimuli together. For example: chocolate followed by a light, a needle prick followed by a smell, etc. You take a mouse and put it in a blue room. You let him wander and explore the room.

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