BIOL 112 Lecture 10: DENT LECTURE 10 Gene Regulation.pdf

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BIOL 112 Full Course Notes
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BIOL 112 Full Course Notes
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All cells in your body share the same alleles of the same genes. Cells appear different because they express different genes. Common is all types of cells: housekeeping genes (i. e. rna polymerase) genes that all cells must express that are necessary for basic functions of metabolism, transcription etc. The main diff. between cells in diff. tissues is that they transcribe diff. subsets of genes. The ability of the rna polymerase to begin transcription is controlled. Accessory proteins that recognize regulatory dna sequences are involved. Promoters includes everal elements: gcbox, caat box, tata box . Cells that do not express a protein also do not express the mrna for that protein. Regulation of the transcription of a particular gene: controlling what proteins will be present. What is regulated is the ability of the rna polymerase to initiate transcription, which is determined by the promoter element (in both eukaryotes and prokaryotes) that are used to recognized the beginnings of genes.

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