BIOL 112 Lecture 22: Lecture 22 - Gene Regulation.pdf

58 views4 pages

taupewhale410

24 Jun 2015

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

hans15149 and 39222 others unlocked

BIOL 112 Full Course Notes

Verified Note

27 documents

Document Summary

All cells in the body share the same alleles of the same genes; contain the same genome! But not all cells express all the same genes -> why different tissues have different phenotypes ! Cells appear different because they express different genes ! Necessary for functions such as metabolism, transcription, etc. !- housekeeping genes: genes necessary for the survival of cells and are expressed in all cells ! !- eukaryotic gene regulation takes place at several levels: level of gene transcription (dna is. !- transcription promoter elements: ! being transcribed to rna), post-transcriptionally (rna can be silenced), post-translationally (level of protein after it is synthesized) ! where dna begin to be denatured ! Tata box: located 25 bp upstream of the transcription start site and is the location. Recognition site: sequence recognized by rna polymerase (upstream of the tata box) ! Transcription start site: location form which transcription begins! Similar to prokaryotic regulation of transcription: !

Related Questions

1 DNA sequences found in introns provide [A] amino acid sequence information.

[B] regulatory information.
[C] no known useful information.

[D] structure for the gene.
[E] alternative DNA splicing possibilities.

3. The TATA box is a(n)
[A] sequence close to the promoter region of many genes.
[B] square-shaped sequence.
[C] enhancer consensus sequence.
[D] activator sequence necessary for proper translation.
[E] None of the above

5. Regarding genes and gene expression, which of the following is not a difference between prokaryotes and eukaryotes
[A] Eukaryotic DNA does not contain a TATA box close to the initiation site as does prokaryotic DNA.

[B] In eukaryotes, RNA polymerase requires

'transcription factors'or initiation.

[C] Prokaryotic genes are often grouped together in

operons.

[D] In eukaryotes, the regulation of several genes at once requires common control elements in each of the genes.
[E] There is a diversity of eukaryotic polymerases that is reflected in the diversity of eukaryotic promoters.

10) In eukaryotic cells, a repressor

[A] is made of DNA.
[B] binds to the enhancer region to block transcription. [

C] is located both upstream and downstream from the promoter.
[D] binds to the operator to block RNA polymerase.

[E] binds to a silencer to reduce transcription rates.

Coordinated regulation of genes in eukaryotic cells [A] is the result of positioning the same regulatory sequence in front of each gene.
[B] results from all of those genes being under the control of one promoter.

[C] occurs because related genes all have the same

operons.
[D] occurs because enhancers cause DNA to bend.

1. What reaction is catalyzed by reverse transcriptase and used in the laboratory to generate cDNA?

a. transcription of RNA to DNA

b. transcription of DNA to RNA

c. conversion of ribonucleotides into deoxyribonucleotides

d. translation of RNA to DNA

e. conversion of a ribonucleotide to a DNA double helix

2. In eukaryotic cells, _________determine the amount of mRNA arising from a particular gene.

a. transcriptional-level controls

b. RNA processing-level controls

c. translational-level controls

d. replication-level controls

e. b and c

3. In eukaryotic cells, _________determine how a primary transcript is converted to mature mRNA

a. transcriptional-level controls

b. RNA processing-level controls

c. translational-level controls

d. replication-level controls

e. a and d

4. In eukaryotic cells, _________determine when a particular mRNA is actually used in protein synthesis.

a. transcriptional-level controls

b. RNA processing-level controls

c. translational-level controls

d. replication-level controls

e. None of the above because protein synthesis takes place immediately

5. Under what circumstances do cells selectively activate and suppress their genes?

a. at different stages of embryonic development

b. in different tissues

c. exposure to different types of stimuli

d. No such circumstances exist in natureâcells express all their genes throughout life.

e. a, b and c

6. Which statement about the control of gene expression is FALSE?

a. A single gene may be controlled by different transcription factors.

b. A single transcription factor may be necessary for the expression of different genes.

c. Each cell type has a characteristic pattern of gene transcription, which is determined by the particular complement of transcription factors contained in that cell.

d. Expression of protein genes is primarily controlled in nucleoli

e. Control of gene transcription is complex and influenced by various circumstances.

7. What is thought to maintain X chromosome inactivation in females?

a. DNA acetylation

b. DNA methylation

c. RNA inactivation

d. Histone methylation

e. None of the above because both X chromosomes are active in females and males.

crimsonplatypus494

2. In eukaryotic cells, _________determine the amount of mRNA arising from a particular gene.

a. transcriptional-level controls

b. RNA processing-level controls

c. translational-level controls

d. replication-level controls

e. b and c

3. In eukaryotic cells, _________determine how a primary transcript is converted to mature mRNA

a. transcriptional-level controls

b. RNA processing-level controls

c. translational-level controls

d. replication-level controls

e. a and d

4. In eukaryotic cells, _________determine when a particular mRNA is actually used in protein synthesis.

a. transcriptional-level controls

b. RNA processing-level controls

c. translational-level controls

d. replication-level controls

e. None of the above because protein synthesis takes place immediately

5. Under what circumstances do cells selectively activate and suppress their genes?

a. at different stages of embryonic development

b. in different tissues

c. exposure to different types of stimuli

d. No such circumstances exist in natureâcells express all their genes throughout life.

e. a, b and c

6. Which statement about the control of gene expression is FALSE?

a. A single gene may be controlled by different transcription factors.

b. A single transcription factor may be necessary for the expression of different genes.

c. Each cell type has a characteristic pattern of gene transcription, which is determined by the particular complement of transcription factors contained in that cell. d. Expression of protein genes is primarily controlled in nucleoli

e. Control of gene transcription is complex and influenced by various circumstances.

7. What is thought to maintain X chromosome inactivation in females?

a. DNA acetylation

b. DNA methylation

c. RNA inactivation

d. Histone methylation

e. None of the above because both X chromosomes are active in females and males.

periwinklehorse209

BIOL 112 Lecture 22: Lecture 22 - Gene Regulation.pdf

BIOL 112 Full Course Notes

Document Summary

Get access

Related Documents

BIOL 112 Lecture Notes - Lecture 22: Tata Box, Transcription Factor Ii D, Tata-Binding Protein

BIOL 112 Lecture 10: DENT LECTURE 10 Gene Regulation.pdf

BIOL 112 Lecture Notes - Lecture 22: Dicer, Caat Box, Zygosity

Related Questions