BIOL 1010 Lecture Notes - Lecture 6: Endocrine System, Nucleolus, Gtpase

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Cells can communicate via signaling molecules (can be called ligands, neurotransmitters, hormones etc. ) Sometimes through direct contact called: cell touching. Can communicate by bumping into each other called cell-to-cell recognition. Synapse uses neurotransmitters, releases from first and stimulates the second neuron. Cell usually part of a gland will release a hormone into the blood and will move far away into different part of the body to interact with other cells. Regardless of distance the arrival will trigger cell signaling: ligand will bind to receptor protein, message will be released into the cell, response (cell will do something) Signal molecule will always bind to a receptor. Receptor is almost always located in the cell membrane. The expectation to that is when the receptor is located inside the cell (cytoplasm) This mostly happens in steroids ligands because they are hydrophobic, -sex hormones are mad from cholesterol, once the receptor binds to hormone they form a complex and will move into nucleolus.

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