PSYC 355 Lecture Notes - Lecture 12: Nicotinic Acetylcholine Receptor, Choline, Adenylyl Cyclase

• School: Concordia University
• Department: Psychology
• Course: PSYC 355
• Professor: All

Document Summary

Lecture 12 : signal transduction receptors and second messengers. Signal transduction changes the way a neuron functions. Something that the receptor, while it is bound, activates. Invented stupid gadgets that were overly complex to accomplish a very simple everyday task. These complex gadgets are exactly like the way second messengers are linked to receptors. Everything in second messengers always leads to calcium. Ligand = anything that binds to a receptor (usually a neurotransmitter but can be a drug) The signalling cell is releasing neurotransmitter (the ligand) which is now binding to the receptor and changing the target cell. You can change the target cell chemically by activating a second messenger. Detection of a molecule on the surface of one cell by receptor on another other, and opening up the other sodium channel. Direct transfer of small molecules through a gap junction activated happen in the cell, there has to be a response. One cell is activated then the other is.