BIOL 467 Lecture Notes - Lecture 17: Bub1B, Chek2, Rna Interference
Document Summary
Biol 467 lecture 17 presentation with the aaaaaaaaah girl. Presentation increased mt assembly rates influence chromosomal instability in colorectal cancer cells. One of the hallmarks is genomic instability. Many tumors in highly advanced stages show extreme genomic instability, and sin is an extreme form of genomic instability. We have whole chromosomes that have been passaged into a cell incorrectly or large rearrangements, translocations, deletions that have occurred. Other sort of hallmarks, activated growth signaling, evading cell death and senescence, limitless replicative potential, dna damage, dna replication stress, Already kind of talked about this but the idea that. Ca(cid:374)(cid:272)e(cid:396)s ha(cid:448)e (cid:1005)(cid:1004)(cid:1004)(cid:859)s (cid:1005)(cid:1004)(cid:1004)(cid:1004)(cid:859)s of (cid:373)utatio(cid:374)s. Ras mutations are common in pancreatic cancers, but not in glioblastomas. All cancers share features in common, but the molecular signature could vary, as long as it gives rise to these features. Genetic instability is common in metastatic tumors.
