BIOL 461 Lecture Notes - Lecture 19: Design Patterns, Zygote, Splicing Factor

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24 Apr 2018
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Biol 461 lecture 19 week 10 friday 21/03/2018 sex determination. Almost all eukaryotes / all organisms that do sexual reproduction undergo sex determination. Drosophila chromosomes are the initial signal. Drosophila have heterogametic where males are the heterogametic gender. Sex determination is a genetic problem because of the chromosomal basis for the signal. Germ line: cells giving rise to the gametes set apart from the soma and distinguished from the somatic development. Imbalance of x to autosomes difference in dosage of x chromosomes has to be compensated (genetic phenomenon) adjusting for that dosage difference and preventing aneuploidy (imbalance in the balance from x to autosomes) Varied the amount of x to autosome ratio. Normal situation: 2 x chromosomes and 2 of each of the autosomal chromosomes (2nd, 3rd and 4th(cid:895) (cid:455)ou get a fe(cid:373)ale, x(cid:863)autoso(cid:373)e ratio is (cid:1005) In a metafemale that has 3 xs still develops as a female,

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