NEUR 3202 Lecture Notes - Lecture 2: Resting Potential, Mecamylamine, Bromine

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8 Mar 2016
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What are the 2 precursors of acetylcholine and how are they. How are the vesicles loaded with acetycholine in the axon. Vessicles are loaded with acetylcholine by a transport protein in the. What drug can block vessicular ach transport and what. The two precursors of acetycholine are choline which comes mainly. Choline aceytl transferase is synthesized within the cell body in the rough endoplasmic reticulum and is transferred to the nerve terminal via axoplasmic transport. The rate of acetycholine is controlled by the availability of its precursor and the rate of cell firing. (cid:1) (cid:1) terminal ? (cid:1) (cid:1) vesicle membrane called vesicular ach transport (vacht) (cid:1) (cid:1) happens ? (cid:1) (cid:1) (cid:1) Decrease of ach in the vesicles but an increase in the level of ach in the cytoplasm. Vesamicol does not affect the rate of ach synthesis. (cid:1) The drug that blocks vessicular ach is called vesamicol.

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