NEUR 3202 Lecture Notes - Lecture 2: Pyridostigmine, Cholinesterase, Physostigmine
Document Summary
Diffusion of acetylcholine across the synaptic cleft and binding of. The movement of sodium ions into the muscle cell results in. Calcium ions enter the presynaptic terminal and cause vesicles to. Presynaptic neuron activated causes ach to be released into synapse (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) and opens ion channels (cid:1) (cid:1) Acetylcholine is rapidly broken down to acedic acid and choline in the. The choline is reabsorbed by the presynaptic terminal and combined. Ach is formed in a single step from two precursors. Choline (comes mainly from fat in our diet & also produced in liver) Synthesis of choline: essential nutrient that is widely distributed in foods in the form of. Foods richest in phosphatidycholine are beef liver, egg yolks and soya. Free choline: beef liver, iceberg lettuce, peanut butter, peanuts and (cid:1) (cid:1) (cid:1) (cid:1) Phosphatidycholine and as free choline (cid:1) (cid:1) cauliflower (cid:1) (cid:1) (cid:1) metabolism of sugars and fats) (cid:1) (cid:1) (cid:1)
