NEUR 2201 Lecture Notes - Lecture 16: Basilar Membrane, Tectorial Membrane, Extracellular Fluid
2 Jan 2019
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Lecture 16 cellular aspect of auditory and somatosensory receptors. List signaling cascades from cilia to cochlear neurons. Distinguish hair cell movement and membrane potentials. Understand the distinction between fast and slowly adapting receptors. Describe proprioceptive mechanisms in the muscle spindle. Differentiate gpcr and trp in nociceptive processing. Understand how these interact and lead to sensitization. Frequency of sound waves measured in hz. Encoding sounds: soundwaves are converted to fluid waves in mammalian cochlea, fluid waves cause vibration of the basilar membrane, hair cells sit on the basilar membrane. The heads of the hair cell sit in a high [k+] low [na+] fluid the scala media (kinda like the extracellular fluid) The basilar membrane is the one tha moves. Basilar membrane parts: apex - low frequency (on the inside, base - high frequency (on the outside) Note: when the cilia are pushes up and bent, it causes a mechanical action which opens channels and allows k+ to come in.
