NEUR 2P36 Lecture Notes - Lecture 10: Phantom Limb, Ventral Posterior Nucleus, Posterior Column

• School: Brock University
• Department: Neuroscience
• Course: NEUR 2P36
• Professor: Dawn Good

Document Summary

Mechanical senses respond to pressure, bending, or other distortions of a receptor. Accomplished by mechanoreceptors (movement of corpuscles & disks) In skin subcutaneous tissue, dermis, epidermis. Discriminates roughness/smoothness; hair follicle receptors at base of hairs) Therefore, can adapt or habituate response (ex. Warm (free nerve endings c fibres) Responds to relative, not absolute, temperature change. Acute pain (free nerve endings- a fibres) Chronic pain (free nerve endings- c fibres) Chronic responds to change in pressure (ex. Pain stimulation of free nerve endings results in the release of: glutamate. A(cid:374)d i(cid:374) se(cid:448)ere pai(cid:374), gluta(cid:373)ate & su(cid:271)sta(cid:374)(cid:272)e p, as (cid:449)ell as hista(cid:373)i(cid:374)es a(cid:374)d gro(cid:449)th fa(cid:272)tor to assist healing/inflammation. A combination of physiological and psychological functions: Similar physiological threshold across individuals; different responses. Natural opiates (endorphins), excessive physical strai(cid:374) (cid:894)ru(cid:374)(cid:374)er(cid:859)s high(cid:895) Reduce edema, block chemical releases, particularly c. Stimulating the release of glutamate & substance p: