HLSC 3P90 Lecture Notes - Lecture 19: Infectious Mononucleosis, Pericardial Fluid, Pericarditis

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Inner serosal layer: adheres to the outer wall of the heart. Composed of a single layer of mesothelial cells. Parietal pericardium: fibrous outer layer, formed by backward reflected visceral layer. A thick film of pericardial fluid separates the two layers. A thick film of pericardial fluid separates the two layers: 15 to 50 ml. Fixes the heart within the mediastinum (central compartment of the thoracic cavity: limiting motion. Prevents the spread of infection from the adjacent lungs. Inflammation of the layers of the pericardium most common affliction of the pericardium. Non-infectious: post-myocardial infarction, uremia, connective tissue diseases, drug-induced, neoplastic pericarditis. Viral infections = influenza, hepatitis b, infectious mononucleosis: patients usually recover by the time serous test results come in, most common manifestation of cardiovascular disease in aids patients. Reactivation of organism in mediastinal lymph node which spreads into the pericardium. Can extend directly from a site within the lungs. Perforating trauma to the chest (e. g. , stab wound)

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