HLSC 2F95 Lecture Notes - Lecture 3: Skeletal Muscle, Acetylcholine, Titin

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Cells are short, branched, striated, with only one nucleus. They cannot regenerate intercalated discs are where cells join together. Cells branch out into 2 different arms striations are due to the overlap in some filaments. Cells are short, spindle-shaped, non striated with one central nucleus. They can divide and regenerate, unlike cardiac cells. Base of hair follicles, walls of blood vessels, lining the urinary bladder, respiratory, circulatory, digestive and reproductive tracts start wide and go into narrow ends. Incapable of cell reproduction, hypertrophy, myosatellite cells can reproduce for muscle repair. Functions of skeletal muscle: produce skeletal movement, maintain posture and body position, support soft tissue (diaphragm, regulating entering and exiting of material, maintain body temperature (working out) Multinucleate (each muscle cell has hundreds of nuclei) Majority of the volume in a muscle fibre (cell) Made up of sarcomeres joined end to end sarcomere is causing the striations.

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