HLSC 2F95 Lecture Notes - Lecture 3: Sliding Filament Theory, Endoplasmic Reticulum, Muscle Fascicle

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Cells are short, branched & striated, one nucleus. Cells are short, spindle shaped, non-striated, one central nucleus. Base of hair follicles, walls of blood vessels, lining the urinary bladder, respiratory, circulatory, digestive, and reproductive tracts. Myosatellite cells can reproduce for muscle repair. Cells are long, cylindrical, striated & multinucleated. Regulate entering and exiting of material (swallowing, going to the bathroom) Perimysium: divides muscles into sections called fascicles. Multinucleate (each cell has hundreds of nuclei) Muscle fibers run parallel to each other. Myosatellite cells (assist in repair and regeneration) Majority of the volume in a muscle fiber (cell) Make up of sarcomeres joined end to end. Made up of myofilaments: actin: thin protein filaments. like 2 ropes that loop together to form a filament. Each has an active site with tropomyosin on top. Anchored to z line: myosin: thick protein filaments. has a tail and a head which has 2 that can move due to the hinge region.

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