HLSC 1F90 Lecture Notes - Lecture 9: Lipo Language, Apoptosis, Metastasis

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Cancer cells will divide even they do not receive appropriate signals, also do not obey the signals to stop dividing; they can continue to divide indefinitely. Nucleus- chromosomes - genes (alteration in gene called mutation) Tumour suppressors, you have 2, if one is mutated the other still works, if both are not working they cannot stop with tumours. Tumours emit signals that say "feed me" and blood vessels become connected to it, cells can metastasize through the blood vessels and invade blood supply. Some die when they enter blood supply or hit vessel walls, others destroyed by the immune system (cancer cells don"t do this) Leave blood vessel and invade another part of the body by dividing. All cancer cells are really a variety of cells with different reaction to different drugs, so one treatment may not kill all of them and they will divide and spread again.

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