HLSC 1F90 Lecture Notes - Lecture 22: Lignan, Red Meat, Osteocyte
13 Oct 2016
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Document Summary
Make no bones about it, osteoporosis threatens the health and well being of canadians . Quality of life: risk of re-fracture: 1 in 3 within 1 year, mortality: 28% of women with hip fracture die within 1 year. Risk factors for osteoporosis: genetics family history, small-boned , no physical activity, early menopause, loss of estrogen, some medications, corticosteroids, anticonvulsants, smoking, alcohol (>2 drinks/day, excessive caffeine, other nutritional inadequacies, aging! Assessment of bone health: humans, animal models, developmental changes, response to interventions. Dexa: higher bone mineral density, bmd (g/cm2, amount of bone mineral in a given area, spine, femur. Quantitative computed tomography: bone structure predicts bone strength, trabecular separation, trabecular number. Materials testing system: amount of force a bone withstands before fracture, surrogate measure of fracture risk. Bone health is a lifelong process: fetal life, childhood, adolescence, adulthood. Peak bone mass: maximum amount of bone that you"ll ever have in your life (25: genetics, physical activity, nutrition.
