BIOL 2P03 Lecture Notes - Lecture 8: Atp Hydrolysis, Microfilament, Screencast
17 Apr 2017
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Week 8 screencast cell organization and movement: microfilaments ii. Cellular contents often need to be moved from one location of the cell to another. Duplicated chromosomes transported to opposite poles of cell during mitosis. Immune cells migrating to regions containing micro-organisms. The cytoskeleton plays an important role in cell movement: microfilament assembly/disassembly can be used to cellular structures that are attached to f-actin, microfilaments and microtubules are also used as tracks for motor proteins. These motor proteins move along microfilaments and microtubules to transport their cargo. Microfilaments ii: movement of cellular cargo by actin-based motor proteins. Cocked" position (3) the myosin head, now containing adp and pi, binds to actin (4) pi is released from myosin and the head bends toward the tail region, pulling actin in this direction. Power stroke" (5) adp is then released from myosin. Myosin binds tightly to actin: once atp binds, myosin releases actin and another cycle begins.
