BIOL 2P03 Lecture Notes - Lecture 8: Microfilament, Screencast, Signal Transduction
17 Apr 2017
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Week 8 screencast cell organization and movement: microfilaments i. Proteins located in based on their assigned. The cytoskeleton is a of proteins consisting of: Intermediate filaments in a specific fashion locations shape appropriate regions functions the cytoskeleton filamentous network. The cytoskeleton is a dynamic system that can reorganize itself to meet the changing needs of the cell. Microfilament structure: microfilaments are made up of the protein actin, monomers of actin are globular and are known as g-actin, g-actin monomers can be polymerized into filamentous structures known as f- actin. G-actin monomers non-covalently bind to each other to form f-actin. The g-actin monomers that make up f-actin each contain an atp/adp binding site. The orientation of these binding sites differs at each end of f-actin. F-actin is therefore said to be polarized. The polymerization of g-actin to form f-actin can be studied in vitro. Purified atp-g-actin is present in solution at a defined concentration.
