BIOL 2P03 Lecture Notes - Lecture 7: Inositol, Transmembrane Domain, Cell Signaling
5 Apr 2017
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Document Summary
Cells are in constant communication with each other and with their environment: must be able to detect appropriate signals and respond to them. In multicellular organisms, cell signalling is required for: organismal development, organization into tissues, co-ordination of activities, control of growth and division. In single cell organisms, cell signalling is required for adaptation to changes in environment. Focus on: signals, receptors, intracellular transduction pathways. Many different signals can be present in a cell"s environment: often more than one signal is available at any given time. Physical signals: photons of light, heat, mechanical disruption. Chemical signals: most common type of signal, range from simple gases (02) to steroids (estrogen) to proteins (insulin) Signals can originate from outside of the organism (exogenous: photons of light, odors, medications, invading micro-organisms. Signals can also be generated internally (endogenous: divided into endocrine, paracrine, autocrine and plasma membrane- attached protein signals chemical signals signaling called a hormone into bloodstream distant target.
