BIOL 1F25 Lecture Notes - Lecture 3: Mptp, Striatum, Indirect Pathway Of Movement
29 Sep 2016
School
Department
Course
Professor
Document Summary
Occurs only after repeated testing that consistently supports the hypothesis over many conditions, usually by many researchers working independently. Theory is accepted as the best explanations for how things work in nature. Ohm"s law for electric circuits: voltage = current x resistance) 1 female, 3 males ages: 26 - 42 years all had history of heroin abuse (3 months to 14 years) 2 obtained new heroin in san jose, july 1st overtime) symptoms as severe as advanced parkinson"s disease (develops. Substantia nigra" in the brain student died, autopsy showed a loss of nerve cells in synthesis : ziering et al, j organic chemistry 1947. Nerve cells project substantia nigra and release dopamine in the striatum. The cells degenerate and die in patients with. Dopamine is necessary for movement because it acts in striatum to: Activate the direct pathway that facilitates movement. Inhibit the indirect pathway that inhibits movement. Patients in california injected themselves with mppp or mptp.
