BIOL 1113 Lecture Notes - Lecture 17: Genetic Counseling, Sample Size Determination, Color Blindness
12 Dec 2017
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Problems with humans: frequently used for humans, but humans are useless in providing pedigree information. Ian sterling 40-year pedigree for polar bears based on fur. Could say what lineages produced more children or survived more: 1. Increased generation time wait longer to have children. Decreased progeny not a big sample size to see what is going on: 3. Pedigrees are : most often applied to humans, 1. Ways to follow how heritable traits/diseases get passed on from one generation to the next: 3. Bigger with higher numbers of children bigger the pedigree you can get, better results: 2. Can identify mode of trait inheritance often interested in mode of inheritance. Interpreting: 4 possible modes" or patterns of inheritance (almost exclusively, 1. Autosomal dominant: x-linked (sex) recessive, x-linked dominant. Procedure: what is mode of inheritance in this pedigree, 1. Choose mode see whether you can make pathway work: 2. Look for contradictions has to all make sense: 4.
