PHAR2210 Lecture Notes - Lecture 13: Forensic Toxicology, Exposome, Ebers Papyrus
Document Summary
Toxicology is the study of the adverse effects of chemical, physical or biological agents on people, animals, and the environment. 2020, >159 million unique chemicals: organic + inorganic registered in chemical abstract service registry, > 15,000 added daily. 2020: 350 000 agents in current widespread use in global economy: >60,000 chemicals poorly understood . 2017, global chemical production ~ us. 7 trillion: us: billion, europe: billion, asia-pacific: billion. Ebers papyrus (~1500 bc: many egyptian recipes for poisons (e. g. prussic acid from peach kernels, arsenic, opium, etc, hebrew bible: For the arrows of the almighty are in me: my spirit drinks their poison . Job 6:4 (esv), c. 6th c bc (?) We only prepare, socrates, just as much as we deem enough. (i. e. hemlock, contains neurotoxin 2- propylpiperidine: mithridates vi of pontus (132-63 b. c. , used prisoners as subjects to test poisons and antidotes, and reportedly consumed a mixture of.
