PHAR 303 Lecture Notes - Lecture 1: Shennong, Mithridates Vi Of Pontus, Clinical Toxicology
27 Jan 2016
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Toxicology: the study of the adverse effects of xenobiotics on biological and. Xenobiotic: any substance that is foreign to a biological system. Toxic substances can be classified according to why the chemicals exist: o o o o o o o. Actions of poisons/toxins that would not be used as therapeutic agents o. Effects of chemicals on the environment - indirect effects on human health e. g. arsenic is a toxin that people used to use as a drug. Emperor shen nung is the father of chinese medicine. He wrote pen tsa"o - the great herbal or chinese materia medica 2735. Ebers papyrus (egypt, ~1500 b. c. ) o o o. First to articulate principles of clinical toxicology relating to bioavailability in therapy and overdosage sure he didn"t get poisoned. Was scared of being poisoned so he wanted to take antidotes to make. Claimed to have discovered mixture of antidotes against all poisons. Treated himself with a mixture of 36 such chemicals.
