BIOS1171 Lecture Notes - Lecture 12: Thermoreceptor, Spinothalamic Tract, Proprioception
22 Aug 2018
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Receptors & sensation: receptor carries in signal from stimulus to cns to create a sensation. Cutaneous receptors: location: mucosa wet lining of body cavities, nociceptors are in all body tissues except cns. Mechanoreceptors: make new skin cells at the bottom layer of the epidermis; these skin cells then migrate up to the surface as they age; eventually this skin is shed and process continues. Transduction: conversion of energy in external world to electrochemical energy in nerve, deformation of skin opens na+ channels, causing depolarization, press on skin, open na+ channels, na+ flows down concentration gradient and into the cell, causing depolsarisation. Receptors potential: aka generator potential, potentials are graded: Skin surface: will generate ap (not all or nothing, as intensity increases receptor. Receptive field: region of sensory surface in which indentation changes receptor"s ap rate, size depends on receptor"s depth, region of skin in which a stimulus makes a receptor respond.
