BIO1022 Lecture Notes - Lecture 8: Microbiology, Antibiotics, Bacterial Vaginosis
13 Oct 2018
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Document Summary
Microbes: have major impact on human health ; < 1 % of all microbes cause disease. Microbiology - how bacteria, viruses, parasites, fungi cause disease using integrative approaches to study how bacteria, virus, parasites, fungi cause disease. Microbes: help maintain balance of nature, may be beneficial, essential to many human processes: foodstuffs, antibiotics, biotechnology. Types of microbes: bacteria/archaea - single cell, algae/protozoa/fungi - single/multicellular viruses - acellular. Structural and biochemical differences allow us to design antimicrobial agents (antibiotics) Selective toxicity- target components of the bacteria that are not present in our eukaryotic cells e. g. penicillin inhibits peptidoglycan synthesis in the bacterial cell wall. Major groups of archaea: methanogens (produce methane, thermophiles (like it hot, halophiles (like it salty) Two part name: first genus ;second species. Example: escherichia coli e. coli or e. coli. Microscopic examination of bacteria difficulties: small size use high powered 100 x objective with oil immersion lens, lack of contrast between cells and background.
