FOOD20003 Lecture Notes - Lecture 28: Hypoglycemia, Broccoli, Pyridoxal
28 Jun 2018
School
Department
Course
Professor
Riboflavin
(B2)
• Involved in energy
metabolism
• Flavin
mononucleotide
(FMN) and flavin
adenine dinucleotide
(NAD) are the
reduced coenzyme
form
Milk products,
including
yoghurt and
cheese
Enriched and
wholegrains
Liver
Not destroyed
by cooking
Deficiency
• Inflammation of
the membranes
of the mouth,
skin, eye and the
GI tract
• Inflamed eyelids,
sensitivity to light,
reddening of the
cornea
• Sore throat and
cracks and
redness at the
corners of the
mouth
• Painful, smooth
and purplish red
tongue
• Skin lesions
covered in
greasy scales
Ariboflavinosis
No toxicity levels
known
Niacin
(B3)
• Involved in glycolysis
& TCA, lipid oxidation
and other enzyme
reactions
• Nicotinamide
adenine dinucleotide
(NAD)
• Nicotinamide
adenine dinucleotide
phosphate (NADP)
Milk
Eggs, meat,
poultry and fish
Wholegrains and
enriched breads
and cereals
Nuts and all
protein-
containing foods
Treating food
with alkaline à
release bound
niacin and
Deficiency
• dermatitis,
dementia, death
• Diarrhoea,
abdominal pain,
vomiting
• Inflamed,
swollen, smooth
and bright red
tongue
• Depression,
fatigue, loss of
memory and
headache
Disease: pellagra
Toxicity
Document Summary
Riboflavin (b2: involved in energy metabolism, flavin mononucleotide (fmn) and flavin adenine dinucleotide (nad) are the reduced coenzyme form. & tca, lipid oxidation and other enzyme reactions: nicotinamide adenine dinucleotide (nad, nicotinamide adenine dinucleotide phosphate (nadp) Treating food with alkaline release bound niacin and. Deficiency: inflammation of the membranes of the mouth, skin, eye and the. Gi tract: inflamed eyelids, sensitivity to light, reddening of the cornea, sore throat and cracks and redness at the corners of the mouth, painful, smooth and purplish red tongue, skin lesions covered in greasy scales. Deficiency: dermatitis, dementia, death, diarrhoea, abdominal pain, vomiting, inflamed, swollen, smooth and bright red tongue, depression, fatigue, loss of memory and headache. Toxicity: precursor = increases its bio- availability tryptophan. Part of coenzyme a involved in energy metabolism. Pyridoxal, pyridoxamine and pyridoxine can all be coveted to the active coenzyme form: pyridoxal phosphate (plp, b6) Participates in reactions involving amino acid group transfer and decarboxylation.
