BIOL10002 Lecture Notes - Lecture 5: Disulfide, Alpha And Beta Carbon, Protein C

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21 Jul 2018
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Each has a carboxyl functional group and an amino functional group attached to the same carbon atom, called the alpha carbon. Also attached to the alpha carbon atom are a hydrogen and a side chain, r group. 5 amino acids have electrically charged (ionised) side chains at ph levels typical of living cells. These side chains attract water (are hydrophilic) and attract oppositely charged ions of all sorts. They are also hydrophilic and attract other polar or charged molecules. 7 amino acids have side chains that are nonpolar and thus hydrophobic. In the watery environment of the cell, these hydrophobic groups may have cluster together in the interior of the protein. 3 amino acids - cysteine, glycine, proline - are special cases, although the side chains of the latter two are generally hydrophobic. The cysteine side chain, which has a terminal -sh group, can react with another cysteine side chain in an oxidation reaction to form a covalent bond.

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