BIO SCI 97 Chapter Notes -Sister Chromatids, Prophase, Cohesin

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Mitosis is the cell division process that produces two daughter cells that are exact replicas of the parent cell. Precise mitosis is essential to form a multicellular organism from a single cell zygote. In somatic (non-reproductive) cells chromosomes are present in pairs. The number of chromosomes is the diploid number (2n) The haploid chromosome number includes one of each chromosome pair (n: kinetochore microtubules embed in the kinetochore at the centromere of each. 2. chromatid, and are responsible for chromosome movement. Polar microtubules extend toward the opposite pole of the centrosome and contribute to cell elongation and cell stability. By the end of prometaphase, kinetochore microtubules are bound to each kinetochore. Metaphase chromosomes are 10,000-fold condensed compared to the onset of prophase; these chromosomes are pulled toward each centrosome by the kinetochore microtubules. The opposing forces align the chromosomes along the metaphase plate. The tension created by the pull of the kinetochore microtubules is balanced by sister chromatid cohesion.

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