Biology 1002B Chapter Notes - Chapter 1-7: Mobile Genetic Elements, Reverse Transcriptase, Antiviral Drug

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Major outcomes for cycles 1 and 2 (term test) Characteristics of viruses and why they are generally not considered alive a. Cannot reproduce on own, dependent on other living beings, no metabolism, etc. Why are viral infections so difficult to cure with drugs, and exceptions to this general principle a. Viruses mutate randomly and often making it difficult to synthesize appropriate/working drugs. Yes they are obligate parasites as they are dependent on other living organisms to reproduce. It has been thought that a free living organism lost ability to metabolize and broke off and gave rise to virus. )mobile genetic elements gained ability to enter/exit cells. Hiv is retro virus so it needs reverse transcription ( which has no proofreading allowing lots of mutation) Hiv goes rna -> dna -> protein disobeying central dogma, we can target this step and attack hiv at this stage. Characteristics of hiv that affect drug design a.

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